Figure 4. Significant modular analysis and functional enrichment analysis based on the PPI network. (A) Construction of a PPI network using a total of 51 prognosis-associated DEIRGs. (B) The most significant module subgroup of the hub genes, identified by MCODE plug-in, contains ten genes. (C) Module 2 contains ten hub genes. (D) Module 3 contains four hub genes. (E) Module 4 contains three hub genes. (F) Functional enrichment analysis of the 27 hub genes in the PPI network.