Research Paper Volume 13, Issue 14 pp 18669—18688
Plasma metabolites changes in male heroin addicts during acute and protracted withdrawal
Figure 2. Obvious metabolic abnormalities during acute heroin withdrawal. (A) PLS-DA score plot of plasma samples obtained from the 3 groups. (B) OPLS-DA score plot showing separation by phenotype between healthy controls and acute heroin withdrawal. (C) OPLS-DA score plot showing separation by phenotype between long-term heroin withdrawal and acute heroin withdrawal. (D) OPLS-DA scores plot showing separation by phenotype between healthy controls and long-term heroin withdrawal. (E) The heatmap of differential metabolites between the 3 groups.