Figure 1.CQ induces the apoptosis and inhibits the viability and proliferation of OS cells. (A) The OS cell viability at 24 h, 48 h, and 72 h after treated with CQ (n = 3). (B) The IC50 value at 24 h and 48 h in 143B and U-2OS cells (n = 3). (C) The colony formation assay showed that the proliferation of OS cells was inhibited gradually by CQ with the increasing of concentration (***p < 0.001; n = 3). (D) Flow cytometry showed that CQ could regulate apoptosis of OS cells (***p < 0.001; n = 3). All the data were expressed as the mean ± SD.
