Research Paper Volume 13, Issue 8 pp 10891—10919

Figure 2. Body weight, body composition, body length, and food intake. (A) Development of body weight during 20 weeks of dietary intervention (NCD, HSD or HFD). (B) Body weight at baseline (week 0). (C) Body weight after 20 weeks of dietary intervention. (D) Lean mass at baseline (week 0). (E) Lean mass after 20 weeks of dietary intervention. (F) Fat mass at baseline (week 0). (G) Fat mass after 20 weeks of dietary intervention. (H) Exemplarily measured body length in male and female adult (mean age 10 weeks) APP23 and WT mice. (I) Mean daily food intake averaged over the entire intervention and across mice occupying the same cage. Data are represented as box (25^th to 75^th percentile) with median and whiskers from minimum to maximum. Black asterisks indicate significant differences between groups (*: p<0.05; **: p<0.01; ***: p<0.001), gray asterisk indicates a statistical trend towards significance (p<0.1) according to nonparametric ANOVA-type statistics (A), ordinary 2-way ANOVA with Tukey post-hoc test (C, G, I), multiple contrast Tukey-type test (E), or nonparametric t-test (B, D, F, H). n_{Week 0 WT}=35, n_{Week 0 APP23}=31, n_{NCD WT}=15, n_{NCD APP23}=9, n_{HSD WT}=10, n_{HSD APP23}=14, n_{HFD WT}=10, n_{HFD APP23}=10; for body length: n_WT=8, n_APP23=11.