Research Paper Volume 13, Issue 9 pp 12766—12779

Morphine may act via DDX49 to inhibit hepatocellular carcinoma cell growth

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Figure 1. Effect of morphine on HCC cell proliferation, invasion and migration. The HCC cell lines QGY-7703 and SMMC-7721 were treated with morphine (0, 0.01,10, or 1000 μm/L) for 72 h. (A, B) Cell proliferation was assessed by MTT assay. (C, D) Migration of cells was assessed in a transwell assay. (E, F) Invasion by cells was assessed in a transwell assay. *P < 0.05, **P < 0.01.