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Online ISSN: 1945-4589

Research Paper|Volume 13, Issue 8|pp. 12031–12045

Low magnitude vibration alleviates age-related bone loss by inhibiting cell senescence of osteogenic cells in naturally senescent rats

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Figure 8.Changes in the SIRT1/p53/p21 axis in osteogenic cells after LMV. (A) BMSCs were treated with LMV and were harvested to detect the protein levels of SIRT1, p53, and p21 using western blotting $(\overline{x}\pm s,\text{n}=3)$; (B) Osteoblasts were treated with LMV and were harvested to detect the protein levels of SIRT1, p53, and p21 using western blotting $(\overline{x}\pm s,\text{n}=3)$; (C) Osteocytes were treated with LMV and were harvested to detect the protein levels of SIRT1, p53, and p21 using western blotting $(\overline{x}\pm s,\text{n}=3)$. *P < 0.05 vs. old female rats.