Research Paper Volume 13, Issue 8 pp 11942—11953
Activation of GPR30 with G1 inhibits oscillatory shear stress-induced adhesion of THP-1 monocytes to HAECs by increasing KLF2
Figure 6. Agonism of GPR30 using its specific agonist G1 suppressed oscillatory shear stress (OSS)-induced adhesion of THP-1 cells to human aortic endothelial cells (HAECs). HAECs were exposed with OSS (5 dyn/cm2) in the presence or absence of 5, 10 μM G1 for 24 h. Attachment of THP-1 cells to HAECs was determined (*, #, $, P<0.01 vs. previous column group, N=5).