Research Paper Volume 13, Issue 8 pp 11860—11876
Genetic landscape of breast cancer and mutation tracking with circulating tumor DNA in Chinese women
Figure 1. Low-frequency somatic mutations detected in DMI-tagged ctDNA from Chinese breast cancer patients. Mutational profiles derived from DMI-tagged ctDNA from stage I (blue), II (deep blue), III (yellow), and IV (red) breast cancers. Each column represents one patient. Different colors represent different types of mutations. Green and orange colors represent mutations and CNV, respectively. Each row represents one gene. The top bar graph denotes the number of mutations detected in each patient. The sidebar represents the proportion of patients with a mutation in a certain gene. CNV, copy number variation; ctDNA, circulating tumor-derived DNA; DMI, digital molecular identifier.