Research Paper Volume 13, Issue 8 pp 11150—11169

The neuroprotection of deproteinized calf blood extractives injection against Alzheimer's disease via regulation of Nrf-2 signaling

class="figure-viewer-img"

Figure 1. DCBEI protects HT22 cells against L-Glu-induced damage. HT22 cells were pre-incubated with DCBEI (4 mg/mL or 8 mg/mL) for 3 h, and co-treated with L-Glu for a further 24 h. (A) DCBEI increased cell viability. (B) DCBEI inhibited apoptosis. DCBEI attenuated the activation of caspase-3/7 (C), caspase-8 (D) and caspase-9 (E). Data are expressed as a percentage of corresponding control cells and means ± S.D. (n = 6). ## P < 0.01 and ### P < 0.001 vs. CTRL, * P < 0.05, ** P < 0.01 and *** P < 0.001 vs. L-Glu-treated cells.