**Figure 2.** **Microbial analyses.** (**A**) The central point represents the root of the tree (bacteria), and each ring represents the next lower taxonomic level (phylum to genus). The diameter of each circle represents the relative abundance of the taxon. (**B**) The different bacterial genera between mice^{control} and mice^{BCCAO} using linear discriminant analysis effect size (LEfSe) analysis, linear discriminant analysis (LDA) score > 3.0, *P* < 0.05 unadjusted; n=15.