Figure 5 — Functional analysis of POLD1 p.ser605del variant: the aging phenotype of MDPL syndrome is associated with an impaired DNA repair capacity

Research Paper|Volume 13, Issue 4|pp. 4926–4945

Functional analysis of POLD1 p.ser605del variant: the aging phenotype of MDPL syndrome is associated with an impaired DNA repair capacity

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Figure 5.Western blot analysis of Polδ from MDPL and WT HDFs after 1 Gy-X-irradiation. (A) Western blot and (B) densitometric analysis of Polδ nucleus/cytoplasm ratio protein levels after 1 Gy-X-irradiation in WT-HDFs. (**P<0.01). (C) Western blot and (D) densitometric analysis of Polδ nucleus/cytoplasm ratio protein levels after 1 Gy-X-irradiation in MDPL-HDFs. (**P<0.01). Data are presented as means ± SD.