Expression of Concern
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
Research Paper Volume 13, Issue 4 pp 6041—6054
Long non-coding RNA CERS6-AS1 facilitates the oncogenicity of pancreatic ductal adenocarcinoma by regulating the microRNA-15a-5p/FGFR1 axis
Figure 6. miR-15a-5p inhibition abolishes the anti-oncogenic actions of CERS6-AS1 knockdown in PDAC cells. (A) RT-qPCR analysis confirmation of miR-15a-5p expression in PANC-1 and SW1990 cells treated with miR-15a-5p inhibitor or NC inhibitor. (B, C) miR-15a-5p inhibitor or NC inhibitor, together with si-CERS6-AS1, was cotransfected into PANC-1 and SW1990 cells. Cell proliferation and apoptosis were detected by CCK-8 assays and flow cytometry analysis, respectively. (D, E) The migration and invasion of the cells described above were measured by Transwell cell migration and invasion assays. *P < 0.05 and **P < 0.01.