Figure 6 — Blockade of Indoleamine 2, 3-dioxygenase 1 ameliorates hippocampal neurogenesis and BOLD-fMRI signals in chronic stress precipitated depression

Research Paper|Volume 13, Issue 4|pp. 5875–5891

Blockade of Indoleamine 2, 3-dioxygenase 1 ameliorates hippocampal neurogenesis and BOLD-fMRI signals in chronic stress precipitated depression

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Figure 6.IDO1 genetic ablation ameliorates neurogenesis in mice under CUMS treatment. (A, C) Immunostaining and the relative fluorescence intensity of the DCX in the hippocampus of WT and Ido1^-/-groups. (B, D) Immunostaining and the relative fluorescence intensity of the Nestin in the hippocampus of WT and Ido1^-/-groups. (scale bar 100 μm). n = 6 mice/group. Bars represent mean±SEM. * p< 0.05, **p< 0.01.