Research Paper Volume 13, Issue 4 pp 5804—5823
Macrophage migration inhibitory factor activates the inflammatory response in joint capsule fibroblasts following post-traumatic joint contracture
Figure 4. Inhibition of MIF in the lesion area attenuated posterior joint capsule inflammation and fibrosis. (A) Expression of MIF (red) in the posterior joint capsule was assessed via immunostaining at 0 d, 3 d and 3 d after injection of 4-IPP. (B) Immunostaining of CD68-positive macrophages (green) in the posterior joint capsule. (C) HE staining of the posterior joint capsule. (D) Masson staining of the posterior joint capsule. Scale bars, 20 μm.