Research Paper Volume 13, Issue 5 pp 6634—6661

Figure 5. CysLT₁R deficiency alleviates neuroinflammation in APP/PS1 mice hippocampus. (A) GFAP⁺ astrocytes in hippocampal sections from different groups were detected. Scale bar = 50 μm. (B) The percentage of GFAP⁺-area was quantified. (C) CD68⁺ microglia in hippocampal sections from different groups were detected. Scale bar = 50 μm. (D) The percentage of CD68⁺-area was quantified. (E) IL-6 and (F) TNF-α in mice hippocampus were assessed by ELISA. All values are expressed as mean ± SEM, n = 4-6, ^#P<0.05, ^##P<0.01, ^###P<0.001 vs. APP/PS1 mice.