Figure 5. The effect of energy reduction and calcium supplementation on 2h-insulin, and HOMA-IR adjusted for age, gender, smoking, drinking, regular exercise, and BMI. (A) Comparison of HOMA-IR changes between ERGs and NERGs. (B) Comparison of HOMA-IR changes between CSGs and NCSGs. (C) Comparison of HOMA-IR changes among CG, ERG, CSG, and ER-CSG. (D) Comparison of Gutt index changes between ERGs and NERGs. (E) Comparison of Gutt index changes between CSGs and NCSGs. (F) Comparison of Gutt index changes among CG, ERG, CSG, and ER-CSG. Note: P-value for the difference in the joint effect of intervention and time.