Research Paper Volume 13, Issue 1 pp 1332—1356

Figure 2. IHC stain and the prognosis value of CCDC170, IRE1α and XBP1s in breast cancer tissues. (A) Representative IHC staining of CCDC170, IRE1α and XBP1s. Scale bar: 50μm. (B) The correlation between CCDC170 and IRE1α levels in breast cancer tissues (r = 0.233, P = 0.020). 1, 2 represented low expression (0-2 staining index) and high expression (3-12 staining index) respectively. n = 100 cases. (C, D) The CCDC170 high-expression group exhibited better DFS (P = 0.037), but no significance in OS (P = 0.183). (E, F) The expression of IRE1α showed no significance in OS (P = 0.530) and DFS (P = 0.094). (G, H) The expression of XBP1s showed no significance in OS (P = 0.678) and DFS (P = 0.377).