Figure 5.Cdc20 overexpression abrogated Notch-1 shRNA-mediated antineoplastic effects. (A) Viability was examined in cells cotransfected with Notch-1 shRNA and Cdc20 cDNA. *P < 0.05 vs control shRNA, # P < 0.05 vs Notch-1 shRNA or Cdc20 cDNA. (B) Apoptosis was examined in osteosarcoma cells after Notch-1 shRNA and Cdc20 cDNA cotransfection.
