Figure 3. The top 20 hub genes selected from the PPI networks. (A) The PPI network of the upregulated significant DE-mRNAs. (B) The PPI network of the downregulated significant DE-mRNAs. (C) The top 20 hub genes of the upregulated significant DE-mRNAs. (D) The 20 hub genes of the downregulated significant DE-mRNAs.