Figure 9 — Atorvastatin improves motor function, anxiety and depression by NOX2-mediated autophagy and oxidative stress in MPTP-lesioned mice

Research Paper|Volume 13, Issue 1|pp. 831–845

Atorvastatin improves motor function, anxiety and depression by NOX2-mediated autophagy and oxidative stress in MPTP-lesioned mice

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Figure 9.Atorvastatin rescues the expression of antioxidant stress Nrf2, HO-1 and NQO-1 (A–D) by inhibiting NOX2 in MPTP mice. The results are expressed as ^*p < 0.05 or ^**p < 0.01 or ^***p < 0.001; NS indicates no significance compared to MPTP/atorvastatin/NOX2-shRNA (-/-/-). The results are expressed as ^#p < 0.05 or ^##p < 0.05 compared to MPTP/atorvastatin/NOX2-shRNA (+/-/-).