Research Paper Volume 13, Issue 1 pp 460—476
Dihydromyricetin promotes longevity and activates the transcription factors FOXO and AOP in Drosophila
Figure 5. DHM induces autophagy in Drosophila. (A) The LysoTracker staining in the midguts of control and DHM-treated flies. The number of the lysosomes in the midguts of control and DHM-treated flies counted in per microscope field of view. (p=0.000023, n=6, t-test). Average number of LysoTracker-stained puncta in fly midguts isolated from control or DHM pretreated flies is presented (±SEM) (B) The relative expression levels of atg1, agt8a and atg8b in control and DHM-treated flies (p=0.5024, p=0.0013, p<0.000001 t-test, n=3).