Figure 2.Binding modes of oleacein mimetics to mTOR. Left panels. Graphical representation of the binding modes of the computationally-predicted oleacein mimetics to the catalytic cavity of mTOR. The black, red, and purple arrows indicate the location of the aromatic rings in the binding modes #1, #2, and #3, respectively. Right panels. Graphical representation of the binding modes of parental oleacein and selected oleacein mimetics with anti-CSC activity (Figure 4, 5) to the catalytic cavity of mTOR.
Figure 2 — Mimetics of extra virgin olive oil phenols with anti-cancer stem cell activity | Aging
