Figure 4. Cell migration and invasion of SNK-1 cells treated with PBS (control), HMSNs, BTZ (75 nM), BTZ@HMSNs (containing 75 nM of BTZ) by Transwell assay. Scale bar equals 5 nm. BTZ, bortezomib; HMSNs, hollow mesoporous silica nanospheres. The differences between groups were analyzed by one-way ANOVA followed by multiple comparison with Tukey test. *P < 0.05. Values are means ± SD.