Silencing hTERT attenuates cancer stem cell-like characteristics and radioresistance in the radioresistant nasopharyngeal carcinoma cell line CNE-2R

Kaihua Chen; Ling Li; Song Qu; Xinbin Pan; Yongchu Sun; Fangzhu Wan; Binbin Yu; Lei Zhou; Xiaodong Zhu

doi:doi:10.18632/aging.104167

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Research Paper Volume 12, Issue 24 pp 25599—25613

Silencing hTERT attenuates cancer stem cell-like characteristics and radioresistance in the radioresistant nasopharyngeal carcinoma cell line CNE-2R

Figure 3. hTERT silencing promoted apoptosis. (A) The apoptosis rates after irradiation at 0 Gy and 4 Gy; (B) Histogram of the apoptosis rate in each group (* indicates P<0.05 compared with hTERT-shRNA cells, while ** indicates P<0.01 compared with hTERT-shRNA cells); (C) Expression of apoptosis-related proteins in each group after irradiation at 4 Gy.