Sevoflurane postconditioning reduces myocardial ischemia reperfusion injury-induced necroptosis by up-regulation of OGT-mediated O-GlcNAcylated RIPK3

Jing Zhang; Peng Yu; Fuzhou Hua; Yanhui Hu; Fan Xiao; Qin Liu; Dan Huang; Fumou Deng; Gen Wei; Wei Deng; Jianyong Ma; Wengen Zhu; Jiru Zhang; Shuchun Yu

doi:doi:10.18632/aging.104146

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Research Paper Volume 12, Issue 24 pp 25452—25468

Sevoflurane postconditioning reduces myocardial ischemia reperfusion injury-induced necroptosis by up-regulation of OGT-mediated O-GlcNAcylated RIPK3

Figure 3. SPC up-regulated the expression of O-GlcNAc and OGT proteins. (A) Representative protein images of O-GlcNAc, OGT and OGA from all groups were shown. (B) Quantitative analysis of O-GlcNAc, OGT and OGA proteins were performed. n = 3 /group. The columns and errors bars represent means ± SD. * P < 0.05 vs. SHAM group; # P < 0.05 vs. IR group.