Steroid 5 alpha-reductase 3 (SRD5A3) promotes tumor growth and predicts poor survival of human hepatocellular carcinoma (HCC)

Qicong Mai; Dafeng Sheng; Chengcong Chen; Qing Gou; Meng Chen; Xiaoting Huang; Heng Yin; Xiaoming Chen; Zide Chen

doi:doi:10.18632/aging.104142

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Research Paper Volume 12, Issue 24 pp 25395—25411

Steroid 5 alpha-reductase 3 (SRD5A3) promotes tumor growth and predicts poor survival of human hepatocellular carcinoma (HCC)

Figure 8. Down-regulation of SRD5A3 suppresses HCC cell growth in vivo. (A, B) Growth curve of the xenograft tumors (two-way ANOVA analysis). (C, D) Images and weight of xenograft tumors in sh-SRD5A3 and sh-NC groups (unpaired t-test). Three mice per group. NC, negative control. Error bar, mean with standard deviation. *, P value < 0.05.