Steroid 5 alpha-reductase 3 (SRD5A3) promotes tumor growth and predicts poor survival of human hepatocellular carcinoma (HCC)

Qicong Mai; Dafeng Sheng; Chengcong Chen; Qing Gou; Meng Chen; Xiaoting Huang; Heng Yin; Xiaoming Chen; Zide Chen

doi:doi:10.18632/aging.104142

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Research Paper Volume 12, Issue 24 pp 25395—25411

Steroid 5 alpha-reductase 3 (SRD5A3) promotes tumor growth and predicts poor survival of human hepatocellular carcinoma (HCC)

Figure 2. SRD5A3 is generally highly expressed in HCC tumor tissues compared to non-HCC liver tissues. SRD5A3 expression in HCC tumor tissues and non-HCC liver tissues were shown for the (A) GSE22058, (B) GSE25097, (C) GSE36376, (D) GSE63898, (E) GSE64041 and (F) TCGA(LIHC) datasets (unpaired t-test). SRD5A3 expression in HCC tumor tissues and adjacent non-HCC liver tissues (peri-HCC) were shown for the (G) GSE54236, (H) GSE64041 and (I) TCGA(LIHC) datasets ((unpaired t-test)). SRD5A3 mRNA level was shown as log2 copy number units. LIHC, liver hepatocellular carcinoma.