Research Paper Volume 12, Issue 24 pp 25120—25137
Apelin protects against ischemia-reperfusion injury in diabetic myocardium via inhibiting apoptosis and oxidative stress through PI3K and p38-MAPK signaling pathways
Figure 7. Examination for expression of PI3K, eNOS, iNOS and p38MAPK. (A) The blotting bands and statistical analysis for PI3K, p38MAPK, eNOS and iNOS expression examined by western blot assay. **P<0.01, ***P<0.001 represent the values compared to the ND-GFP group. ##P<0.01, ###P<0.001 represent the values compared to the Ad-GFP group. ND-GFP: Non-diabetes ischemia reperfusion injury rats injected with recombined lentiviral vector expressing GFP; ND-Apelin: Non-diabetes ischemia reperfusion injury rats injected with Ad-recombined lentiviral rector expressing Apelin; Ad-GFP: Diabetes ischemia reperfusion injury rats injected with Ad-recombined lentiviral vector expressing GFP. Ad-Apelin: Diabetes ischemia reperfusion injury rats injected with Ad-recombined lentiviral rector expressing Apelin.