Figure 5.HPV11 PsV infections are reduced by autophagy. (A, B) Western analysis of LC3 in NHEKs (A) or HaCaT cells (B) during HPV11 PsV entry with or without rapamycin pre-treatment. LC3-II levels are normalized to β-Actin and uninfected vehicle control, and expressed as the mean and standard deviation from three biological independent experiments. (C) Infectivity assays using PsVs containing a luciferase expression vector. Luciferase activity is normalized by cell viability and presented as the mean and standard deviation from three biological independent experiments. Significant differences were identified by Student’s t test. *, P < 0.05; ***, P < 0.005.
