Research Paper Volume 12, Issue 21 pp 21518—21543

Oncostatin M expression and TP53 mutation status regulate tumor-infiltration of immune cells and survival outcomes in cholangiocarcinoma

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Figure 5. Identification of Immune Related Hub Gene OSM of CCA Patients with and without TP53 Mutations. (A) Volcano plot of TP53wild and TP53mutant group from TCGA dataset; (B) DEGs PPI network of TP53wild and TP53mutant group; (C) Top10 immune related genes were filtered from TP53 mutation associated DEGs by calculating the nodes scores of genes; (D) Overall survival of the Top10 immune related genes analyzed by KM curve analysis and log-rank test.