Research Paper Volume 12, Issue 20 pp 20308—20331
TRIM28 is a distinct prognostic biomarker that worsens the tumor immune microenvironment in lung adenocarcinoma
Analysis of DEGs according to TRIM28 expression in LUAD patients. (A) Volcano map showing all the genes associated with TRIM28 in LUAD. (B, C) Volcano maps showing all the DEGs based on TRIM28 expression. (D) Venn diagram showing the number of common DEGs. (E, F) Top 14 GO enrichment terms (E) and top 13 KEGG enrichment terms (F) for all DEGs, analyzed in Metascape. (G) Associations among the top 10 cluster enrichment terms analyzed by Metascape, displayed as a network. An edge links terms with a similarity score > 0.3. (H) Gene Set Enrichment Analysis according to the expression of TRIM28 in TCGA. GO, gene ontology; DEGs, differentially expressed genes; LUAD, lung adenocarcinoma; GSEA, Gene Set Enrichment Analysis; TCGA, The Cancer Genome Atlas; GSE, Gene Expression Omnibus data series.