Research Paper Volume 13, Issue 1 pp 241—261
In situ self-assembly of Au-antimiR-155 nanocomplexes mediates TLR3-dependent apoptosis in hepatocellular carcinoma cells
Figure 1. MiR-155 is overexpressed in HCC tissues and cells. (A) miR-155 expression in HCC and adjacent non-cancer tissues (ANCT) was measured by qRT-PCR (n=30; P<0.05 vs. ANCT). (B) qRT-PCR analysis of miR-155 transcripts in L02, HepG2, and SMMC-7721 cells (n=3; **P<0.01, *P<0.05; HepG2/SMMC-7721 vs L02 cells). (C) Kaplan-Meier analysis showing the association between miR-155 expression and overall survival (OS) in HCC patients. (D) ROC curve and AUC statistics indicating the diagnostic performance of high miR-155 expression on HCC. Error bars represent the SD of the mean from at least three independent experiments.