Research Paper Volume 12, Issue 15 pp 15546—15555

Figure 1. GCDC enhances chemoresistance in HCC cells. (A–D) Cell viability was detected using the CCK-8 assay. *P<0.05, **P<0.01. (E–H) Cell apoptosis was analyzed by flow cytometry. *P<0.05. (I–J) GCDC enhanced the ability of chemoresistance of HCC cells in vivo. Huh7 cells (5×10⁶) were pretreated with GCDC and then were implanted in the right subcutaneous armpit area of nude mice. Then the cisplatin (4mg/kg) were injected in tumor every 3 days. After 27 days, the mice were sacrificed and the weight of the tumor was measured.*P<0.05, **P<0.01.