Modeling mtDNA hypermethylation vicious circle mediating Aβ-induced endothelial damage memory in HCMEC/D3 cell

HaoChen Liu; Hong Zhang; Yixuan Zhang; Sheng Xu; Huimin Zhao; Hua He; XiaoQuan Liu

doi:doi:10.18632/aging.103699

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Research Paper Volume 12, Issue 18 pp 18343—18362

Modeling mtDNA hypermethylation vicious circle mediating Aβ-induced endothelial damage memory in HCMEC/D3 cell

Figure 7. (A) The simulation for change of mtDNA methylation, AKG, MMP, and cell vitality in AKG supplement treated cells. (B) The simulation for change of mtDNA methylation, AKG, MMP, and cell vitality in DNMT inhibitor treated cells.