Research Paper
Exosomal miR-211 derived from cancer stem cells promotes cancer progression by activating autophagy in NSCLC
Figure 6. Exo-miR-211 derived from CSC promoted tumorigenesis and autophagy of NSCLC cells in vivo. CSCs stably transfected with miR-211 or AMO-211 or NC were constructed, and the nude mice were injected A549 or H1299 cells incubated with a mixture of CSCs (n = 6 for each group). (A) Growth of tumor xenografts in nude mice. n=6, *p<0.05. (B) Representative tumors excised from xenografts in nude mice and tumor weight. n=6, *p<0.05. (C) The protein expression of BCL-W and autophagy related protein p62 and LC3I/II were analyzed by western bolt in isolated tumors. n=6, *p<0.05.