Research Paper
Exosomal miR-211 derived from cancer stem cells promotes cancer progression by activating autophagy in NSCLC
Figure 4. miR-211 directly targeted on BCL-W in NSCLC cells. (A) TargetScan predicted data between miR-211 and BCL-W. (B) qRT-PCR analyzed the expression of BCL-W in A549 and H1299 cells transfected with miR-211 or AMO-211. n=6, *p<0.05. (C) qRT-PCR analyzed BCL-W expression of A549 and H1299 cells incubated with TC or CSC exosomes. n=6, *p<0.05 vs TC exo. (D) Luciferase assay for WT and mutant BCL-W activity in HEK293 cells transfected with miR-211 or AMO-211. n=6, *p<0.05. (E) Luciferase assay for WT and mutant BCL-W activity in HEK293 cells incubated with TC or CSC exosomes. n=6, *p<0.05 vs TC exo.