Research Paper Volume 12, Issue 19 pp 19022—19044
Target RNA modification for epigenetic drug repositioning in neuroblastoma: computational omics proximity between repurposing drug and disease
Summary for schematic diagram and RNA modification regulators (RNA-MRs) in NBL. (A) The schematic diagram of target mining and drug screening in this study. (B) A schematic view of location and types of predominant RNA modification. W: writer (methyltransferase), R: reader (RNA-binding protein), E: eraser (demethylase). TRDMT1: formerly DNMT2. (C) The protein interaction network among RNA-MRs using STRING analysis. KIAA1429: VIRMA. (D) The detailed schematic diagram for determination of NBL severity signature.