Research Paper Volume 12, Issue 17 pp 17209—17223
CircRNA circ_0072995 promotes the progression of epithelial ovarian cancer by modulating miR-147a/CDK6 axis
Figure 2. Knockdown of circ_0072995 suppressed EOC cell proliferation and migration, induces apoptosis in vitro. (A) Transfection efficiency of circ_0072995 knocking down determined by qRT-PCR. (B) Effect of circ_0072995 and si-circ_0072995 upon EOC cell growth curves as detected by CCK-8 assays. (C, D) The effect of circ_0072995 and si-circ_0072995 on EOC cell migratory and invasive capabilities as detected by wound healing and transwell assays. (E) The effect of circ_0072995 and si-circ_0072995 on EOC cell apoptosis as detected by flow cytometry apoptosis.