Expression of Concern
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This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
Research Paper Volume 13, Issue 10 pp 14482—14498
Sirt1 improves heart failure through modulating the NF-κB p65/microRNA-155/BNDF signaling cascade
Figure 1. Sirt1, NF-κB p65 expression and apoptosis in heart tissues of successfully induced HF rats. (A) Ventricular mass index; (B) Sirt1 mRNA expression, determined using RT-qPCR; (C) Sirt1, NF-κB p65, and NF-κB p65 Ac protein expression assessed by Western blot analysis; (D) Collagen volume faction determined by Masson’s trichrome staining (100 ×); (E) Apoptosis determined by TUNEL staining (200 ×); *p < 0.05 vs. control rats and # p < 0.05 vs. sham rats. Data were expressed as a mean ± standard deviation. Three or more groups were analyzed by one-way analysis of variance (ANOVA) and Tukey's post hoc test. N = 12.