Research Paper Volume 12, Issue 18 pp 18099—18126

Figure 2. Results of the risk of bias and methodological quality indicators for all included studies. Notes: Q, question. Q1: Was the allocation sequence adequately generated and applied?; Q2: Were the groups similar at baseline or were they adjusted for confounders in the analysis?; Q3: Was the allocation to the different groups adequately concealed?; Q4: Were the animals randomly housed during the experiment?; Q5: Were the caregivers and/or investigators blinded from knowledge which intervention each animal received during the experiment?; Q6: Were animals selected at random for outcome assessment?; Q7: Was the outcome assessor blinded?; Q8: Were incomplete outcome data adequately addressed?; Q9: Are reports of the study free of selective outcome reporting?; Q10: Was the study apparently free of other problems that could result in high risk of bias?; Q11: Was it stated that the experiment was randomized at any level?; Q12: Was it stated that the experiment was blinded at any level?; Q13: Was it stated that there was no conflict of interest?; Q14: Was the funding source of the study provided?