Research Paper Volume 12, Issue 17 pp 16951—16962

Figure 1. Effect of Esculentoside A on body, ovary weights and estrus cycle of POF mice. (A, B) Body weight and ovary weight after combination of POF and EA treatment, respectively. POF: Premature ovarian failure (C) Representative picture of estrous cycles in control mice (upper), POF mice (middle) and Esculentoside A-treated mice (lower). Bars represent the average length (day) of proestrus (P), estrus (E), metestrus (M) and diestrus (D) per estrous cycle. (D) The length of estrous cycle of each group. ^*P< 0.05, ^***P < 0.001 vs. Control. ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs. POF.