Research Paper Volume 12, Issue 15 pp 15414—15435
Depletion of exosomal circLDLR in follicle fluid derepresses miR-1294 function and inhibits estradiol production via CYP19A1 in polycystic ovary syndrome
Figure 2. Differentially expressed circRNA analysis. (A) Volcano plot showing the distribution of circRNA differential expression according to their p values and fold-changes. Candidates with p< 0.05 and fold change >= 2 are highlighted in red. (B) Heat map showing hierarchical clustering analysis of circRNA candidates in follicular exosomes isolated from PCOS and control donors.