Research Paper Volume 12, Issue 15 pp 15566—15580
The association between KLF4 as a tumor suppressor and the prognosis of hepatocellular carcinoma after curative resection
Figure 1. KLF4 expression in hepatocellular carcinoma (HCC) tissues and cell lines. (A) KLF4 expression was detected in the mRNA level among five HCC cell lines and one normal liver cell (L02). (B) KLF4 expression was detected in the protein level in six cell lines. The internal control was β-actin. (C) Immunohistochemical results were analyzed by chi-square test to compare the distribution of KLF4 in HCC tumors and adjacent tissues. (D) KLF4 expression was analyzed in tumor and para-tumorous tissues in TCGA tumors. (E) KLF4 expression was exhibited through characteristic photos of immunostaining in HCC tumor and para-tumorous tissues. Image scale= 100μm. P < 0.05 was considered statistically significant, * P < 0.05, ** P < 0.01, *** P < 0.001.