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Online ISSN: 1945-4589
Research Paper
|
Volume 12, Issue 16
|
pp. 16099–16110
IL-21 mediates microRNA-423-5p /claudin-5 signal pathway and intestinal barrier function in inflammatory bowel disease
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Figure 3
(3 of 6)
−
100%
+
Figure 3.
MiR-423-5p could bind with the 3'UTR of
claudin-5.
(
A
) Binding sequences between miR-423-5p and claudin-5 (CLDN5) (
http://www.targetscan.org/cgi-bin/targetscan/vert_72/view_gene.cgi?rs=ENST00000406028.1&taxid=9606&members=miR-423-5p&showcnc=1&shownc=1&shownc_nc=1&showncf1=&showncf2=&subset=1
). The luciferase assay report. n=3. (
B
,
C
) The expression of claudin-5 in colorectal epithelial cell lines. n=4. (
D
) The level of miR-423-5p in colonic mucosa from UC patients and healthy volunteers. n=15. (
E
) Representative images of immunofluorescence staining with claudin-5. *
P
< 0.05, **
P
< 0.01
Figure 3 — IL-21 mediates microRNA-423-5p /claudin-5 signal pathway and intestinal barrier function in inflammatory bowel disease | Aging