Figure 2 — NVD-BM-mediated genetic biosensor triggers accumulation of 7-dehydrocholesterol and inhibits melanoma via Akt1/NF-ĸB signaling

Research Paper|Volume 12, Issue 14|pp. 15021–15036

NVD-BM-mediated genetic biosensor triggers accumulation of 7-dehydrocholesterol and inhibits melanoma via Akt1/NF-ĸB signaling

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Figure 2.NVD-BM inhibits melanoma cell proliferation and migration. (A) A375 cell proliferation when transfected with different NVD-BM concentrations at 24 h. (B, C) The migration rates of 5×10³ A375 and A2058 cells, transfected with pCDH and NVD-BM plasmid were assessed over 36 h by RTCA assay. (*p < 0.05, **p < 0.01, ***p < 0.001)