Figure 4.(A) The expression of hsa_circ_0076690, miR-152 and RUNX2 were measured by qRT-PCR during osteogenic differentiation of hBMSCs. (B) MiR-152 and RUNX2 expression levels were measured by qRT-PCR after transfected with hsa_circ_0076690 in hBMSCs. (C) RUNX2 expression was inhibited by miR-152 mimics and remained constant under miR-152/hsa_circ_0076690 co-overexpression. (D) The expression level of osteogenic-associated biomarkers and ALP activity were detected after transfected with hsa_circ_0076690, miR-152 mimics and miR-152/hsa_circ_0076690 co-overexpression in hBMSCs.
