Research Paper Volume 12, Issue 14 pp 14219—14231

Figure 7. Overexpression of TINCR inhibits CRC growth in vivo. In vivo xenograft experiments (subcutaneous transplantation with lentivectors carrying luciferase reporter and shTINCR/TINCR/scramble) were conducted to analyze the role of TINCR on tumor growth in vivo. (A, B) At 8 weeks after xenografting, tumor growth was determined by bioluminescence, shown by quantification (A), and by representative images (B). (C, D) Tumor growth curve after xenografting of Caco-2 cells (C) and SW480 cells (D). N=5. *p<0.05.