Research Paper Volume 12, Issue 15 pp 15290—15301

Neutrophil depletion enhances the therapeutic effect of PD-1 antibody on glioma

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Figure 2. Tumor-infiltrating neutrophil (TIN) levels increase with tumor grades and in IDH-WT gliomas. (A) In the Sanbo cohort, TIN levels were compared between LGG (n = 52) and glioblastoma (GBM; n = 150) gliomas, and (B) in IDH-mutant (Mut; n = 55) and IDH wild-type (WT; n = 147) gliomas. (C) In the TCGA dataset, TIN levels were compared between LGG (n = 524) and GBMs (n = 153), and (D) IDH-Mut (n = 424) and IDH-WT (n = 234) gliomas.