Research Paper Volume 12, Issue 17 pp 16775—16802
Identification of cardiovascular health gene variants related to longevity in a Chinese population
Figure 2. Stratification analysis of metabolic phenotype of TFPI rs7586970 and ADAMTS7 rs3825807. (A) Correlation analysis of allele frequency of TFPI rs7586970 with metabolic phenotype. The frequency of the rs7586970 T is specifically correlated with the metabolic level of lipids (-) +FBG (-) +BMI (+) in centenarians. The allele frequency of rs7586970 T was significantly increased in the centenarians group. (B) Correlation analysis of allele frequency of ADAMTS7 rs3825807 with metabolic phenotype. The frequency of the rs3825807 A is specifically correlated with the metabolic level of lipids (-) +FBG (-) +BMI (-) in centenarians. (C) Correlation analysis of genotype frequency of TFPI rs7586970 with metabolic phenotype. The rs7586970 recessive model (TT/TC+CC) showed a specific correlation with lipids (-) +FBG (-) +BMI (+) in centenarians.