Research Paper Volume 12, Issue 13 pp 12987—13004
Transcriptome analysis of common and diverged circulating miRNAs between arterial and venous during aging
Figure 3. The enriched functions of deregulated miRNAs between arterial and venous blood samples and their target genes. (A) Bar plot showing the functional association of differentially-expressed miRNAs between arterial and venous plasma from young rats. (B) Bar plot showing the functional association of deregulated miRNAs between arterial and venous plasma from aged rats. (C) Heatmap showing the genes intensively regulated by deregulated genes in young rats and their functional association. The interaction between miRNAs and their target genes is indicated by an orange box, while the presence of the target gene in specific pathways is indicated by a blue box. (D) Heatmap showing the genes intensively regulated by deregulated genes in aged rats and their functional association. The number beside the function terms indicates the number of differentially expressed miRNAs associated with the corresponding function.